Print
Health Care

Two Wilmington Firms Involved In Moderna's Phase 3 COVID Vaccine Study

By Christina Haley O'Neal, posted Jul 30, 2020
Two Wilmington companies are supporting a phase 3 clinical study aimed at developing a vaccine for the new coronavirus.

Wilmington-based PPD Inc. is one of those companies involved in Moderna Inc.'s phase 3 study of its mRNA vaccine candidate against COVID-19, according to a news release.

Cambridge, Massachusetts-based Moderna Inc. and the National Institute of Allergy and Infection Diseases (NIAID), part of the National Institutes of Health, announced this week that the phase 3 trial for the vaccine, known as mRNA-1273, has started.

NIAID and the federal government's Biomedical Advanced Research and Development Authority (BARDA) are providing funding for the trial, stated the release.

The biotechnology company is working with the NIAID and BARDA to develop the study, which is being supported by the government's Operation Warp Speed, a multi-agency initiative consisting of private and public partners that aims to deliver a safe and effective vaccine for COVID-19 by January 2021.

“Congratulations to Moderna on this important milestone. The world is eager for solutions, and we are pleased to support Moderna in progressing its vaccine candidate," David Simmons, PPD’s chairman and CEO, said this week. "The depth of our relationship with Moderna has enabled us to jointly expedite strategy development from the early days of the pandemic and accelerate its COVID-19 program execution.”

On top of PPD's work to support Moderna's phase 3 study, it has also supported the phase 2 study, which completed the enrollment of 600 people at eight research sites within a month, according to the release.

"PPD has contributed an array of clinical development and laboratory services, including strategic expertise to the study design, patient-enrollment epidemiology modeling and biostatistics," stated the release.

The phase 3 trial is expected to include 30,000 participants and take place at 100 clinical research sites selected by Moderna, according to the release.

"The primary endpoint will be the prevention of symptomatic COVID-19 disease. Key secondary endpoints include prevention of severe COVID-19 disease (as defined by the need for hospitalization) and prevention of infection by SARS-CoV-2 regardless of symptomology. SARS-CoV-2 is the virus that causes COVID-19," stated the release.

Moderna "is partnering closely with those sites to ensure that volunteers at increased risk for COVID-19 disease are enrolled in the study" and is working with local communities to reach a diverse population, officials said in the release.

Wilmington is one of those sites, said Phil Dattilo, president of Wilmington-based Trial Management Associates LLC, a clinical management firm.

Trial Management Associates (TMA) is taking part in Moderna's phase 3 study by working with Bart Williams and Will Jones, two physicians at Wrightsville Family Practice, to conduct phase 3 clinical trials in Wilmington.

The company announced in June that it would be part of a phase 3 trial for a potential coronavirus vaccine, but was unable at the time to confirm what the firm it was involved with. 

​“Drs. Williams and Jones are very excited to begin the Phase 3 trial of Moderna’s vaccine here in Wilmington this coming week,” Dattilo said in an email Thursday. “We are continuing to accept people who are interested in participating … We appreciate all of our current volunteers’ patience as we work diligently to schedule the large volume of volunteers for their initial visit.”

Those in the area who would like to participate in the phase 3 trial can email TMA at [email protected]

The group was also selected by Moderna earlier this year to conduct a phase 2 trial for the potential vaccine. Wilmington was one of 10 sites selected by Moderna for the phase 2 trial, which wrapped up earlier this year.

Another company, Pfizer, announced Monday that it had also begun a late-stage coronavirus vaccine study, according to news reports.
Ico insights

INSIGHTS

SPONSORS' CONTENT
Jeremytomlinson enfuse headshot

Repair Or Replace? 7 Signs That You Need A New Computer

Jeremy Tomlinson - Enfuse Technology Solutions
Morton300x300

CFCC's Small Business Center Offers Free Support For Local Business Owners And Entrepreneurs

Jim Morton - Cape Fear Community College
Connorkeller headshot

Patience Pays Dividends

Connor Keller - Live Oak Private Wealth

Trending News

Vantaca Fills HOA Industry Need

Scott Nunn - May 7, 2021

General Aviation Services Business Hiring Ahead Of Busy Season

Christina Haley O'Neal - May 7, 2021

Meet The 2021 CEA Winners

Vicky Janowski - May 7, 2021

Topsail Steamer Continues To Gather Steam

Jenny Callison - May 7, 2021

Meeting Needs In Pender County

Cece Nunn - May 7, 2021

In The Current Issue

Restaurant Owners Cook Up Big Plans

It’s been said that the road to success is always under construction, and the saying rings true for the McDuffie family....


Vaccination 'passports' Come Into Focus

CastleBranch, the Wilmington-based consumer reporting agency, touts its status as “one of the first companies in the world” to issue a COVID...


Wilson Center Springs Back To Life

More than a year after closing its doors to the public due to a worldwide pandemic, Cape Fear Community College’s Wilson Center welcomed gue...

Book On Business

The 2021 WilmingtonBiz: Book on Business is an annual publication showcasing the Wilmington region as a center of business.

Order Your Copy Today!


Galleries

Videos

Trying to Grow a Business?
2020 Health Care Heroes
2020 WilmingtonBiz 100