Print
Health Care

Two Wilmington Firms Involved In Moderna's Phase 3 COVID Vaccine Study

By Christina Haley O'Neal, posted Jul 30, 2020
Two Wilmington companies are supporting a phase 3 clinical study aimed at developing a vaccine for the new coronavirus.

Wilmington-based PPD Inc. is one of those companies involved in Moderna Inc.'s phase 3 study of its mRNA vaccine candidate against COVID-19, according to a news release.

Cambridge, Massachusetts-based Moderna Inc. and the National Institute of Allergy and Infection Diseases (NIAID), part of the National Institutes of Health, announced this week that the phase 3 trial for the vaccine, known as mRNA-1273, has started.

NIAID and the federal government's Biomedical Advanced Research and Development Authority (BARDA) are providing funding for the trial, stated the release.

The biotechnology company is working with the NIAID and BARDA to develop the study, which is being supported by the government's Operation Warp Speed, a multi-agency initiative consisting of private and public partners that aims to deliver a safe and effective vaccine for COVID-19 by January 2021.

“Congratulations to Moderna on this important milestone. The world is eager for solutions, and we are pleased to support Moderna in progressing its vaccine candidate," David Simmons, PPD’s chairman and CEO, said this week. "The depth of our relationship with Moderna has enabled us to jointly expedite strategy development from the early days of the pandemic and accelerate its COVID-19 program execution.”

On top of PPD's work to support Moderna's phase 3 study, it has also supported the phase 2 study, which completed the enrollment of 600 people at eight research sites within a month, according to the release.

"PPD has contributed an array of clinical development and laboratory services, including strategic expertise to the study design, patient-enrollment epidemiology modeling and biostatistics," stated the release.

The phase 3 trial is expected to include 30,000 participants and take place at 100 clinical research sites selected by Moderna, according to the release.

"The primary endpoint will be the prevention of symptomatic COVID-19 disease. Key secondary endpoints include prevention of severe COVID-19 disease (as defined by the need for hospitalization) and prevention of infection by SARS-CoV-2 regardless of symptomology. SARS-CoV-2 is the virus that causes COVID-19," stated the release.

Moderna "is partnering closely with those sites to ensure that volunteers at increased risk for COVID-19 disease are enrolled in the study" and is working with local communities to reach a diverse population, officials said in the release.

Wilmington is one of those sites, said Phil Dattilo, president of Wilmington-based Trial Management Associates LLC, a clinical management firm.

Trial Management Associates (TMA) is taking part in Moderna's phase 3 study by working with Bart Williams and Will Jones, two physicians at Wrightsville Family Practice, to conduct phase 3 clinical trials in Wilmington.

The company announced in June that it would be part of a phase 3 trial for a potential coronavirus vaccine, but was unable at the time to confirm what the firm it was involved with. 

​“Drs. Williams and Jones are very excited to begin the Phase 3 trial of Moderna’s vaccine here in Wilmington this coming week,” Dattilo said in an email Thursday. “We are continuing to accept people who are interested in participating … We appreciate all of our current volunteers’ patience as we work diligently to schedule the large volume of volunteers for their initial visit.”

Those in the area who would like to participate in the phase 3 trial can email TMA at [email protected]

The group was also selected by Moderna earlier this year to conduct a phase 2 trial for the potential vaccine. Wilmington was one of 10 sites selected by Moderna for the phase 2 trial, which wrapped up earlier this year.

Another company, Pfizer, announced Monday that it had also begun a late-stage coronavirus vaccine study, according to news reports.
Ico insights

INSIGHTS

SPONSORS' CONTENT
Mike stonestreet 300x300

Want To Be An Amazing Neighbor? Five Ways To Start (And Some Things To Avoid)

Mike Stonestreet - CAMS (Community Association Management Services)
Dallas headshot 300x300

Not All Strategies Are Created Equal

Dallas Romanowski - Cornerstone Business Advisors
Jasonpathfinder3

Election Fears & Financial Freedom

Jason Wheeler - Pathfinder Wealth Consulting

Trending News

Developer Provides Update On River Place, Other Major Projects

Cece Nunn - Sep 30, 2020

Wilmington Firm Acquires Arizona-based Software Provider

Staff Reports - Sep 29, 2020

ILM Passengers Trending Up; Boston Nonstop Eyed For 2021

Christina Haley O'Neal - Sep 28, 2020

First Watch Prepares For Mayfaire Opening; Independence Mall To Follow

Jessica Maurer - Sep 30, 2020

CEO: A.R.C. Transit's Acquisition Will Boost Firm Growth

Christina Haley O'Neal - Sep 29, 2020

In The Current Issue

Local Internet Access Expands

Recent project announcements by two local internet service providers aim to pave the way for expanding internet access in the region, a tech...


Connecting The Business Community Amid The Shutdowns

This year's WilmingtonBiz Conference & Expo is a little different, but still aims to help the area's business community make vital one-on-on...


Info Junkie: Michealle Gady

Michealle Gady, founder, president and CEO of Atrómitos, an SBA-certified woman-owned management consulting business, shares her tech and in...

Book On Business

The 2020 WilmingtonBiz: Book on Business is an annual publication showcasing the Wilmington region as a center of business.

Order Your Copy Today!


Galleries

Videos

2020 Leadership Accelerator: Virtual Workshops for Real Leaders
2019 Health Care Heroes
August 26, 2019 Power Breakfast: A Healthy Sale?
2019 WilmingtonBiz Expo Keynote Lunch - CEO, nCino, Pierre Naude`